ABSTRACT
Objective:To investigate the effects of a psychological and behavioral intervention on carotid artery stenosis in patients undergoing stent implantation.Methods:Ninety-five patients with carotid artery stenosis who underwent stent implantation in Department of Neurology, The First Affiliated Hospital of Anhui University of Science and Technology (Huainan First People's Hospital) from June 2020 to June 2021 were included in this study. They were randomly divided into observation group ( n = 48) and control group ( n = 47). The control group was given routine preoperative and postoperative treatment and nursing care. The observation group was given perioperative management, which was developed by medical experts to target patient's psychology and behavior, in addition to routine preoperative and postoperative treatment and nursing care. Self-Rating Anxiety Scale (SAS) score, Self-rating Depression Scale (SDS) score, heart rate and blood pressure pre- and post-surgery were compared between the two groups. Results:SAS score, SDS score, heart rate, systolic blood pressure and diastolic blood pressure post-surgery in the observation group were (43.22 ± 3.73) points, (34.71 ± 7.62) points, (63.22 ± 3.73) beats/min, (111.24 ± 8.53) mmHg and (73.43 ± 7.62) mmHg, respectively, which were significantly lower than those in the control group [(44.22 ± 4.12) points, (37.92 ± 6.91) points, (81.98 ± 4.14) beats/min, (130.43 ± 32.21) mmHg, and (78.52 ± 5.51) mmHg, all P < 0.05]. Conclusion:A psychological and behavioral intervention can guide patients to correctly understand carotid artery stenosis, eliminate adverse psychological factors such as fear and depression, and improve the quality of life of patients.
ABSTRACT
The B-cell lymphoma gene 2 (Bcl-2) is considered as the most important inhibiting cell apoptosis control gene,and its expression is up-regulated in asthma.Drug intervention against Bcl-2 affects signal pathways,down-regulates the Bcl-2 expression,and induces programmed cell death.It may become the target of asthma treatment.This article reviews the structure characteristics of the Bcl-2,the mechanism of regulating apoptosis,and its role in asthma.
ABSTRACT
Objective To investigate clinical features , outcomes and prognosis gerontol delirium . Methods Patients with gerontol delirium diagnosed between January 2011 and January 2013 were identified by a retrospective review of records in the Nanjing General Hospital of Nanjing Military Command .Totally 132 patients were included , 59 females and 73 males, with a median age of 71.4 years (range 65-97).The diagnostic criteria were based on the DSM-Ⅳ and Delirium Rating Scale.Dementia, depression, mental retardation and other cognitive dysfunction were excluded .General condition of patients , etiology , clinical features , treatment and prognosis were all performed using the SPSS 20.0 for windows.A P value of <0.05 was considered as significant . Results Disturbance of consciousness were observed in all 132 patients.Old age, coma and serious infection in the course , endotracheal intuba-tion and(or) tracheotomy, a variety of basic diseases all come up with poor prognosis . Conclusion Delirium progresses quickly. Etiological treatment can help to control the conditions of delirium .